P 417 Night blindness due to chronic pancreatitis: Vitamin A deficiency despite oral pancreatic enzyme therapy
نویسندگان
چکیده
B Confirming the diagnosis of night blindness in our patient, the scotopic response in his electroretinogram (ERG) was distinctly reduced while the photopic response was normal. When his blood was examined for a low level of vitamin A as a possible cause for night blindness, we found the value to be reduced below normal (17 pg/dl versus 25-70 pg/dl in normal subjects). Treatment with vitamin A supplement resulted in prompt normalization of vitamin A level (79 pg/dl after two weeks). Symptoms completely disappeared, and the scotopic response in the ERG rehuned to normal.
منابع مشابه
Pancreatic Enzyme Replacement Therapy
Patients with chronic pancreatic insufficiency develop improper digestion due to the lack of digestive pancreatic enzymes. Such patients might complain of diarrhea and multi-nutrient deficiencies. Children with cystic fibrosis are at an increased risk of developing pancreatic insufficiency, while adults can develop chronic pancreatitis due to gallbladder disease or alcohol consumption. Regardle...
متن کاملAnterior Segment Findings in Vitamin A Deficiency: A Case Series
Vitamin A deficiency is a rare but vision threatening disorder in the developed world, which can lead to blindness for severe keratomalacia with cornea scarring and perforation or night blindness due to impaired dark adaptation. Conversely, the disease is quite common in developing countries, as a consequence of chronic malnutrition. The correct diagnosis and therapy with prompt vitamin A suppl...
متن کاملVitamin A treatment for night blindness in primary biliary cirrhosis.
Three patients with late stage primary biliary cirrhosis were found to have appreciable night blindness. Serum vitamin A concentrations were low in all three patients despite regular intramuscular supplementation in two. All patients responded dramatically to high dose oral supplementation, with full recovery of adaptation to dark and visual fields. Oral rather than intramuscular vitamin A supp...
متن کامل[Night blindness and xerophthalmia after surgery for morbid obesity].
CASE REPORT We describe ocular findings due to a vitamin A deficiency in a 50-year-old man. The patient had undergone intestinal bypass surgery two years before. After therapy with oral vitamin A the symptoms improved. DISCUSSION The incidence of morbid obesity is increasing throughout much of the developed world, with intestinal bypass surgery the treatment of choice for most people with the...
متن کاملOral pancreatic enzyme substitution therapy in chronic pancreatitis: is clinical response an appropriate marker for evaluation of therapeutic efficacy?
CONTEXT Malnutrition secondary to pancreatic exocrine insufficiency plays a prognostic role in chronic pancreatitis. Enzyme substitution therapy is generally prescribed to avoid diarrhea and weight loss, although it is unknown whether this is associated with normal absorption of nutrients and a normal nutritional status. OBJECTIVE We aimed to evaluate whether an adequate clinical response to ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Vision Research
دوره 35 شماره
صفحات -
تاریخ انتشار 1995